Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827200 | 0.84 | RAB9A (0.63) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL23602 | 0.83 | RAB9A (1.00) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL13210663 | 0.80 | RAB9A (0.59) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL12263907 | 0.79 | RAB9A (0.58) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL27971154 | 0.78 | F10 (0.73) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL10213378 | 0.78 | L3MBTL1 (0.57) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL10213375 | 0.78 | RAB9A (0.56) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL16017275 | 0.77 | RAB9A (0.53) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL27971290 | 0.76 | RAB9A (0.70) | RAB9ARECQLNPC1MAPTSMN1; SMN2 | |
| SCHEMBL13210725 | 0.76 | RAB9A (0.54) | RAB9ARECQLNPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009954-A2 | METHOD FOR MODULATING CALCIUM ION-RELEASE-ACTIVATED CALCIUM ION CHANNELS | SYNTA PHARMACEUTICALS, CORP. (US) | 2005-02-03 | — | — | WO | disclosed |