Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302332 | 1.00 | HPGD (0.34) | HPGDTSHRTGM2CES1IDO1 | |
| SCHEMBL8303880 | 0.82 | CHRM1 (0.42) | TGM2CES1IDO1TDO2CHRM1 | |
| SCHEMBL8880752 | 0.82 | MAOB (0.41) | TGM2CES1IDO1TDO2MDM2 | |
| SCHEMBL8880601 | 0.82 | CHRM1 (0.42) | TGM2CES1IDO1TDO2CHRM1 | |
| SCHEMBL8880758 | 0.82 | MAOB (0.41) | TGM2CES1IDO1TDO2MDM2 | |
| SCHEMBL27461474 | 0.73 | CHRM1 (0.32) | CHRM1 | |
| SCHEMBL27461472 | 0.73 | CHRM1 (0.32) | CHRM1 | |
| SCHEMBL8880980 | 0.72 | MDM2 (0.40) | TGM2CES1IDO1TDO2MDM2 | |
| SCHEMBL27392795 | 0.71 | TGM2 (0.32) | TGM2CES1IDO1TDO2MDM2 | |
| SCHEMBL27373896 | 0.71 | TGM2 (0.32) | TGM2CES1IDO1TDO2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579968-B1 | 4-Iminoquinolines, processes for their preparation and their use | HOECHST AG (DE) | 1999-09-01 | — | — | EP | disclosed |
| EP-0579968-A1 | 4-Iminoquinolines, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-26 | — | — | EP | disclosed |