Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551312 | 0.85 | KDM4E (0.43) | PIK3CDLMNAALOX15TSHRHSD17B10 | |
| SCHEMBL5551323 | 0.85 | PIK3CD (0.33) | PIK3CDLMNAALOX15TSHRHSD17B10 | |
| SCHEMBL8927900 | 0.84 | KMT2A (0.42) | PIK3CDLMNAHTT | |
| SCHEMBL8560245 | 0.84 | ALDH1A1 (0.43) | ALOX15HTTL3MBTL1 | |
| SCHEMBL26655290 | 0.83 | PIK3CD (0.52) | PIK3CDBRD4 | |
| SCHEMBL26655296 | 0.83 | PIK3CD (0.52) | PIK3CDBRD4 | |
| SCHEMBL7995036 | 0.83 | TSHR (0.41) | SMN1; SMN2LMNAALOX15TSHRHSD17B10 | |
| SCHEMBL4150920 | 0.83 | TSHR (0.41) | SMN1; SMN2LMNAALOX15TSHRHSD17B10 | |
| SCHEMBL8928194 | 0.82 | PDK1 (0.35) | PIK3CDLMNAHTT | |
| SCHEMBL21354258 | 0.81 | TSHR (0.41) | SMN1; SMN2LMNAALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004771-A | EXTRACTED MYCOBACTERIAL SAMPLE IS SUITABLE FOR DETECTION BY CULTURE AND AMPLIFICATION | INTEGRATED RESEARCH TECHNOLOGY, LLC (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0643705-B1 | PROCESS FOR PRODUCING N-beta-g(b)-HYDROXYALKYL-TRI-N-CARBOXYALKYL-1,4,7,10-TETRAAZACYCLODODECANE AND N-beta-g(b)-HYDROXYALKYL-TRI-N-CARBOXYALKYL-1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AND THEIR METAL COMPLEXES | SCHERING AG (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0643705-A1 | PROCESS FOR PRODUCING N-$g(b)-HYDROXYALKYL-TRI-N-CARBOXYALKYL-1,4,7,10-TETRAAZACYCLODODECANE AND N-$g(b)-HYDROXYALKYL-TRI-N-CARBOXYALKYL-1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AND THEIR METAL COMPLEXES | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-03-22 | — | — | EP | disclosed |
| US-5386028-A | Process for the production of N-β-hydroxyalkyl-tri-N-carboxyalkyl-1,4,7,10-tetraazacyclododecane and N-β-hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecane derivatives and their metal complexes | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-01-31 | — | — | US | disclosed |
| WO-1993024469-A1 | PROCESS FOR PRODUCING N-β-HYDROXYALKYL-TRI-N-CARBOXYALKYL-1,4,7,10-TETRAAZACYCLODODECANE AND N-β-HYDROXYALKYL-TRI-N-CARBOXYALKYL-1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AND THEIR METAL COMPLEXES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-12-09 | — | — | WO | disclosed |