Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928194 | 0.90 | PDK1 (0.35) | KMT2ALMNAHTTPDK1PDK2 | |
| SCHEMBL8302334 | 0.84 | PIK3CD (0.38) | LMNAHTTPIK3CD | |
| SCHEMBL13505787 | 0.83 | KMT2A (0.58) | KMT2ALMNAHTTMEN1PIK3CD | |
| SCHEMBL5551312 | 0.81 | KDM4E (0.43) | KMT2ALMNAMEN1PIK3CD | |
| SCHEMBL5551323 | 0.81 | PIK3CD (0.33) | LMNAPIK3CD | |
| SCHEMBL8560245 | 0.80 | ALDH1A1 (0.43) | KMT2AHTTMEN1 | |
| SCHEMBL4150920 | 0.78 | TSHR (0.41) | LMNAHTTPDK1PDK2PDK3 | |
| SCHEMBL7995036 | 0.78 | TSHR (0.41) | LMNAHTTPDK1PDK2PDK3 | |
| SCHEMBL8559141 | 0.78 | ALDH1A1 (0.52) | KMT2ALMNAHTTMEN1 | |
| SCHEMBL8927884 | 0.77 | PDK1 (0.41) | PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5690909-A | USEFUL AS NMR AND X-RAY DIAGNOSTIC AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-25 | — | — | US | disclosed |
| EP-0700393-B1 | MACROCYCLIC METAL COMPLEXES CONTAINING FLUORINE | SCHERING AG (DE) | 1997-10-22 | — | — | EP | disclosed |
| EP-0700393-A1 | MACROCYCLIC METAL COMPLEXES CONTAINING FLUORINE | SCHERING AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027978-A1 | MACROCYCLIC METAL COMPLEXES CONTAINING FLUORINE | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |