Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83816 | 0.84 | TDP1 (0.61) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15085780 | 0.81 | SMN1; SMN2 (0.60) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4252848 | 0.80 | ALDH1A1 (0.36) | TDP1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10036476 | 0.79 | ALDH1A1 (0.71) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1834344 | 0.79 | ACHE (0.56) | HTTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL14280533 | 0.79 | HTT (0.56) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14612631 | 0.79 | TDP1 (0.55) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16450319 | 0.79 | CYP1A2 (0.44) | MAPTFFAR4MAOB | |
| SCHEMBL194091 | 0.78 | ACHE (0.48) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30358269 | 0.77 | SMN1; SMN2 (0.69) | HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101507-A2 | N-SULPHONYLATED AMINO ACID DERIVATIVES AND USE THEREOF AS MATRIPTASE INHIBITORS | CURACYTE CHEMISTRY GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |