Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17159666 | 0.78 | IDO1 (0.43) | SMN1; SMN2NPC1RAB9APKML3MBTL1 | |
| SCHEMBL6075631 | 0.78 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8153911 | 0.77 | IDO1 (0.44) | SMN1; SMN2NPC1RAB9APKML3MBTL1 | |
| SCHEMBL8211813 | 0.76 | L3MBTL1 (0.32) | SMN1; SMN2NPC1RAB9AKMT2APKM | |
| SCHEMBL8789509 | 0.76 | ALDH1A1 (0.30) | ALDH1A1LMNA | |
| SCHEMBL2889854 | 0.75 | MAOA (0.38) | SMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL2889852 | 0.75 | MAOA (0.38) | SMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL8230596 | 0.74 | — | — | |
| SCHEMBL8229019 | 0.74 | — | — | |
| SCHEMBL8791888 | 0.72 | PPARG (0.39) | RAB9AMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729461-B1 | FUNGICIDAL CYCLIC AMIDES | DU PONT (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5977149-A | Dihydrotriazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1995014009-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |