SCHEMBL8303372

SCHEMBL8303372

CCn1ncc(C(=O)Sc2cc(C)c3c(c2C)C(OC)CCO3)c1OS(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8306999 0.87
SCHEMBL8303370 0.74 GAA (0.31)
SCHEMBL8307889 0.73 GAA (0.31)
SCHEMBL8307113 0.73 GAA (0.31)
SCHEMBL8303291 0.67 ALDH1A1 (0.31)
SCHEMBL8134238 0.67 RAB9A (0.32)
SCHEMBL8307541 0.67 BDKRB1 (0.32)
SCHEMBL8941176 0.66 NPC1 (0.30) MEN1KMT2A
SCHEMBL8308195 0.66 ALDH1A1 (0.30)
SCHEMBL8308183 0.66 NPC1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0629623-B1 PYRAZOLE DERIVATIVE IDEMITSU KOSAN CO (JP) 1999-05-19 EP disclosed
US-5587484-A HALOGENATION; OXIDATION; SULFONATION; HERBICIDES IDEMITSU KOSAN CO., LTD. (JP) 1996-12-24 US disclosed
US-5468722-A Herbicides for corn, wheat, barley IDEMITSU KOSAN CO., LTD. (JP) 1995-11-21 US disclosed
EP-0629623-A1 PYRAZOLE DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-12-21 EP disclosed