Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 4/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297144 | 0.80 | RAB9A (0.48) | RAB9APLOD2VNN1L3MBTL1MEN1 | |
| SCHEMBL3195037 | 0.77 | RAB9A (0.56) | RAB9APLOD2VNN1L3MBTL1MEN1 | |
| SCHEMBL784586 | 0.74 | GLA (0.62) | AGBL2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL18975045 | 0.72 | AGBL2 (0.47) | AGBL2RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL27360693 | 0.71 | NPC1 (0.49) | RAB9APLOD2VNN1L3MBTL1PTPN1 | |
| SCHEMBL6339735 | 0.71 | PTPN1 (0.56) | RAB9APLOD2VNN1PTPN1GSK3B | |
| SCHEMBL9470576 | 0.70 | KMT2A (0.44) | VNN1MEN1KMT2ATRPM8GSK3B | |
| SCHEMBL15805590 | 0.69 | AGBL2 (0.47) | AGBL2L3MBTL1MEN1KMT2APOLQ | |
| SCHEMBL16165957 | 0.69 | AGBL2 (0.44) | AGBL2RAB9AL3MBTL1KMT2AKCNQ3 | |
| SCHEMBL26974131 | 0.69 | AGBL2 (0.44) | AGBL2L3MBTL1MEN1KMT2APOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508469-B1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5493024-A | 1,2-DIARYL-2-PROPEN-1-ONE CHEMICAL INTERMEDIATE COMPOUND | DOWELANCO (US) | 1996-02-20 | — | — | US | disclosed |
| US-5324837-A | 3,4-disubstituted-4,5-dihydro-1H-pyrazoles and a method of preparation | DOWELANCO (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0508469-A1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1992-10-14 | — | — | EP | disclosed |