Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297144 | 0.85 | RAB9A (0.48) | NPC1RAB9AHTR7PLOD2MMP1 | |
| SCHEMBL27447528 | 0.82 | NPC1 (0.51) | NPC1RAB9AHTR7PTPN1DRD2 | |
| SCHEMBL26136120 | 0.77 | MMP1 (0.67) | NPC1RAB9AHTR7PLOD2MMP1 | |
| SCHEMBL6201845 | 0.77 | MMP1 (0.54) | NPC1RAB9AHTR7PLOD2MMP1 | |
| Hydrochloric Acid SCHEMBL5752228 | 0.75 | MMP1 (0.51) | NPC1RAB9AHTR7PLOD2MMP1 | |
| SCHEMBL3195037 | 0.73 | RAB9A (0.56) | NPC1RAB9APLOD2MMP1VNN1 | |
| SCHEMBL27365024 | 0.72 | RAB9A (0.55) | NPC1RAB9AHTR7PLOD2L3MBTL1 | |
| SCHEMBL8303473 | 0.71 | AGBL2 (0.47) | NPC1RAB9APLOD2VNN1L3MBTL1 | |
| SCHEMBL26584242 | 0.71 | NPC1 (0.82) | NPC1RAB9AHTR7PLOD2PTPN1 | |
| SCHEMBL10559396 | 0.70 | NPC1 (0.67) | NPC1RAB9AHTR7PLOD2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067426-A | 3,4, N-three replaces-4,5-dihydro-1 h-pyrazole-1-methane amide and they application as sterilant | DOWELANCO (US) | 1992-12-30 | — | — | CN | disclosed |