Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452075 | 0.92 | SLC6A4 (0.45) | ACHEL3MBTL1ARGAATDP1 | |
| SCHEMBL446449 | 0.90 | AR (0.47) | ACHEL3MBTL1ARGAATDP1 | |
| SCHEMBL740256 | 0.88 | CA12 (0.52) | ACHEL3MBTL1ARGAACA12 | |
| SCHEMBL22561630 | 0.87 | ALDH1A1 (0.58) | L3MBTL1ARGAATDP1ALDH1A1 | |
| SCHEMBL22199044 | 0.86 | ACHE (0.52) | ACHEL3MBTL1ARGAACA12 | |
| SCHEMBL5608759 | 0.84 | GAA (0.55) | ACHEL3MBTL1ARGAAFFAR4 | |
| SCHEMBL11855895 | 0.83 | ACHE (0.57) | ACHEL3MBTL1ARGAAALDH1A1 | |
| SCHEMBL11767346 | 0.83 | CA12 (0.59) | ACHEL3MBTL1ARGAACA12 | |
| SCHEMBL12770836 | 0.83 | ACHE (0.48) | ACHEARCA12CA1CA2 | |
| SCHEMBL19175092 | 0.82 | SLC6A4 (0.50) | ACHEL3MBTL1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141439-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-09 | — | — | WO | disclosed |
| EP-2316830-A2 | N-sulphonylated amino acid derivatives and their use as matriptase inhibitors | The Medicines Company (Leipzig) GmbH (DE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2007113327-A2 | FUNGICIDE N-CYCLOPROPYL-SULFONYLAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-10-11 | — | — | WO | disclosed |
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| WO-2004101507-A2 | N-SULPHONYLATED AMINO ACID DERIVATIVES AND USE THEREOF AS MATRIPTASE INHIBITORS | CURACYTE CHEMISTRY GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |