Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303790 | 1.00 | ALDH1A1 (0.35) | ALDH1A1FKBP5KMT2ABCHEDPP4 | |
| SCHEMBL9232966 | 0.81 | KDM4E (0.35) | ALDH1A1F2KDM4EPOLBNPC1 | |
| SCHEMBL9232970 | 0.81 | KDM4E (0.35) | ALDH1A1F2KDM4EPOLBNPC1 | |
| SCHEMBL27532358 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1KMT2ANPSR1POLBNPC1 | |
| SCHEMBL617286 | 0.79 | NPSR1 (0.48) | ALDH1A1FKBP5KMT2ABCHEDPP4 | |
| SCHEMBL2835654 | 0.79 | NPSR1 (0.48) | ALDH1A1FKBP5KMT2ABCHEDPP4 | |
| SCHEMBL8300090 | 0.78 | EPHX1 (0.36) | ALDH1A1KMT2ADPP4HTTPOLB | |
| SCHEMBL8300088 | 0.78 | EPHX1 (0.36) | ALDH1A1KMT2ADPP4HTTPOLB | |
| SCHEMBL8539717 | 0.78 | ATM (0.44) | ALDH1A1NPC1 | |
| SCHEMBL8539711 | 0.78 | ATM (0.44) | ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614986-B1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates | SYNTHELABO (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0565396-B1 | 1-[2-(arylsulfonylamino)-1-oxoethyl]piperidine derivatives, their preparation and use in therapy | SYNTHELABO (FR) | 1998-01-07 | — | — | EP | disclosed |
| EP-0614986-A1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates and their use as synthesis intermediates | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |