Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231126 | 0.79 | PARP1 (0.35) | PARP1 | |
| Hydrochloric Acid SCHEMBL5629042 | 0.77 | PARP1 (0.35) | PARP1 | |
| SCHEMBL9271325 | 0.77 | PARP1 (0.32) | PARP1 | |
| Hydrochloric Acid SCHEMBL6070163 | 0.77 | PARP1 (0.35) | PARP1 | |
| SCHEMBL12644566 | 0.76 | CHRNB2 (0.43) | — | |
| SCHEMBL27688141 | 0.74 | CHRNB4 (0.33) | PARP1 | |
| SCHEMBL11119263 | 0.73 | PARP1 (0.35) | PARP1 | |
| SCHEMBL2636887 | 0.72 | MPO (0.41) | — | |
| SCHEMBL24169127 | 0.71 | CCNT1 (0.33) | BMPR1BPDGFRBKDRACVR1BTGFBR1 | |
| SCHEMBL1074310 | 0.70 | ROCK2 (0.32) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923573-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5905152-A | Preparation of aminomethyl-phenylimidazoles | SCHERING CORPORATION (US) | 1999-05-18 | — | — | US | disclosed |
| WO-1998006716-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1998-02-19 | — | — | WO | disclosed |