Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.51 |
| ▸ | RXRB | P28702 | 17/20 | 0.51 |
| ▸ | RXRG | P48443 | 12/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | C5 | P01031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305905 | 0.85 | RXRA (0.45) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL5210892 | 0.84 | RXRA (0.62) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL8307612 | 0.83 | RXRA (0.43) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL8307646 | 0.82 | RXRA (0.43) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL8305970 | 0.82 | RXRA (0.43) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL8307794 | 0.80 | RXRA (0.46) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL8303845 | 0.79 | RXRA (0.41) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL5211557 | 0.78 | RXRA (0.56) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL7955853 | 0.78 | RXRA (0.48) | RXRARXRBRXRGNR4A2TSHR | |
| SCHEMBL5210730 | 0.77 | RXRA (0.53) | RXRARXRBRXRGNR4A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036882-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |