Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.41 |
| ▸ | RXRB | P28702 | 6/20 | 0.41 |
| ▸ | RXRG | P48443 | 6/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305905 | 0.94 | RXRA (0.45) | RXRARXRBRXRGNR4A2PTGDR2 | |
| SCHEMBL4442406 | 0.87 | SIRT2 (0.38) | RXRARXRBRXRGPTGDR2KDM4E | |
| SCHEMBL8303347 | 0.86 | NR4A2 (0.35) | RXRARXRBRXRGNR4A2PTGDR2 | |
| SCHEMBL4563793 | 0.86 | SIRT2 (0.35) | ALDH1A1MAPT | |
| SCHEMBL8308639 | 0.86 | MAPT (0.35) | KDM4EALDH1A1MAPTHTT | |
| SCHEMBL8304088 | 0.85 | HSD17B10 (0.40) | TSHRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4442084 | 0.85 | SIRT2 (0.34) | ALDH1A1 | |
| SCHEMBL7514117 | 0.85 | SIRT2 (0.34) | ALDH1A1 | |
| SCHEMBL7505595 | 0.85 | PPARG (0.41) | RXRARXRBRXRGFFAR4S1PR1 | |
| SCHEMBL8303146 | 0.85 | CRHR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036882-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |