Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.43 |
| ▸ | RXRB | P28702 | 9/20 | 0.43 |
| ▸ | RXRG | P48443 | 6/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307612 | 0.93 | RXRA (0.43) | RXRARXRBRXRGFFAR4TSHR | |
| SCHEMBL8305905 | 0.86 | RXRA (0.45) | RXRARXRBRXRGFFAR4TSHR | |
| SCHEMBL8307646 | 0.84 | RXRA (0.43) | RXRARXRBRXRGFFAR4TSHR | |
| SCHEMBL8304152 | 0.82 | RXRA (0.51) | RXRARXRBRXRGTSHRKDM4E | |
| SCHEMBL8303845 | 0.80 | RXRA (0.41) | RXRARXRBRXRGFFAR4TSHR | |
| SCHEMBL8307794 | 0.79 | RXRA (0.46) | RXRARXRBRXRGFFAR4TSHR | |
| SCHEMBL5212038 | 0.78 | RXRA (0.60) | RXRARXRBRXRGFFAR4TSHR | |
| SCHEMBL8303347 | 0.77 | NR4A2 (0.35) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL5210892 | 0.77 | RXRA (0.62) | RXRARXRBRXRGTSHRKDM4E | |
| SCHEMBL7508131 | 0.76 | GCGR (0.37) | TSHRALDH1A1MAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036882-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |