Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2151682 | 0.91 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL4248193 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL14464189 | 0.83 | ALDH1A1 (0.79) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL18396735 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL4921368 | 0.80 | ALDH1A1 (0.75) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL30928952 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL1127011 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL85672 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL5058298 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL7814507 | 0.77 | ALDH1A1 (0.66) | ALDH1A1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717738-B1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5880118-A | Substituted oxazine and thiazine oxazolidinone antimicrobials | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| US-5688792-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-18 | — | — | US | disclosed |