Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300516 | 0.75 | ACHE (0.31) | — | |
| SCHEMBL8305411 | 0.68 | KDM4E (0.31) | KDM4ECYP1A2CYP2C19 | |
| SCHEMBL27406701 | 0.68 | APP (0.44) | KDM4ECYP1A2 | |
| SCHEMBL7654639 | 0.67 | CYP19A1 (0.42) | KDM4E | |
| SCHEMBL8522511 | 0.67 | — | — | |
| SCHEMBL8303502 | 0.66 | — | — | |
| SCHEMBL8306226 | 0.64 | — | — | |
| SCHEMBL7658574 | 0.64 | APLNR (0.32) | — | |
| SCHEMBL7660666 | 0.64 | BRS3 (0.32) | — | |
| SCHEMBL8304618 | 0.64 | KDM4E (0.33) | KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936221-A1 | NOVEL 2,4-DIOXOPYRROLIDINE AND 2,4-DIOXOTETRAHYDROFURAN DERIVATIVES AND MEDICINES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | LEAD CHEMICAL COMPANY LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |