SCHEMBL8304527

SCHEMBL8304527

CC(=NO)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.60
ALDH1A1 P00352 2/20 0.60
CTSK P43235 1/20 0.57
LMNA P02545 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CA9 Q16790 1/20 0.46
CASP3 P42574 1/20 0.44
GFER P55789 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
KDM4E B2RXH2 3/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL28010798 0.94 ALDH1A1 (0.52) HPGDALDH1A1CTSKLMNAL3MBTL1
SCHEMBL45278 0.80 LMNA (0.52) HPGDALDH1A1LMNAL3MBTL1CA9
Benzene SCHEMBL28280701 0.80 LMNA (0.52) HPGDALDH1A1LMNAL3MBTL1CA9
SCHEMBL257242 0.80 LMNA (0.52) HPGDALDH1A1LMNAL3MBTL1CA9
SCHEMBL2736631 0.80 LMNA (0.52) HPGDALDH1A1LMNAL3MBTL1CA9
SCHEMBL11235227 0.78 LMNA (0.50) HPGDALDH1A1LMNAL3MBTL1CA9
Water SCHEMBL4312372 0.78 LMNA (0.50) HPGDALDH1A1LMNAL3MBTL1CA9
SCHEMBL27945945 0.78 LMNA (0.50) HPGDALDH1A1LMNAL3MBTL1CA9
SCHEMBL11266105 0.78 LMNA (0.50) HPGDALDH1A1LMNAL3MBTL1CA9
SCHEMBL28059930 0.78 LMNA (0.50) HPGDALDH1A1LMNAL3MBTL1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4597224-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED PRODUCT Toray Industries, Inc. (JP) 2025-08-06 EP disclosed
US-5972959-A Oxime derivatives, their preparation and their therapeutic use SANKYO COMPANY, LIMITED (JP) 1999-10-26 US disclosed
EP-0708098-B1 Oxime derivatives, their preparation and their therapeutic use SANKYO CO (JP) 1999-03-03 EP disclosed
US-5780490-A A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS SANKYO COMPANY, LIMITED (JP) 1998-07-14 US disclosed
US-5703096-A ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR SANKYO COMPANY, LIMITED (JP) 1997-12-30 US disclosed
EP-0708098-A1 Oxime derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1996-04-24 EP disclosed