Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | LDHB | P07195 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063172 | 0.83 | ALDH1A1 (0.37) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL11471358 | 0.77 | DPP4 (0.46) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL4236884 | 0.77 | POLB (0.44) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL18701630 | 0.76 | DAO (0.43) | DAOALDH1A1SMN1; SMN2KMT2AGPR35 | |
| SCHEMBL6492073 | 0.76 | POLB (0.53) | DAOALDH1A1KMT2APOLBTDP1 | |
| SCHEMBL190089 | 0.74 | ALDH1A1 (0.41) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL18701622 | 0.74 | KEAP1 (0.38) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL17398273 | 0.74 | TSHR (0.47) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL20439940 | 0.74 | DAO (0.38) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL8366102 | 0.74 | L3MBTL1 (0.39) | DAOALDH1A1MAPK1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| CN-112375212-A | N-type organic semiconductor material and preparation method and application thereof | 华南理工大学 | 2021-02-19 | — | — | CN | disclosed |
| EP-0695748-B1 | Tetrazolinone herbicides | BAYER AGROCHEM KK (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5589439-A | HERBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0695748-A1 | Tetrazolinone herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0206364-A2 | Heterocyclic amidinoureas | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4565826-A | HYPOTENSIVE, CARDIONASCULAR, ANTIULCER, ANTISECRETORY, GASTROINTESTINAL DISORDERS | WILLIAM H. RORER, INC. (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0078839-A4 | HETEROCYCLIC AMIDINOUREAS. | RORER INTERNAT OVERSEAS INC (US) | 1984-07-25 | — | — | EP | disclosed |
| US-4436911-A | HYPOTENSIVE, ANTISPASMODIC, ANTIULCER, ANTIPARASITIC | WILLIAM H. RORER, INC. (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0078839-A1 | HETEROCYCLIC AMIDINOUREAS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1983-05-18 | — | — | EP | disclosed |
| WO-1982004047-A1 | HETEROCYCLIC AMIDINOUREAS | RORER INT OVERSEAS (US) | 1982-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | CDK1, CDKN1A, CDKL1 | DAO 4301/4885ALDH1A1 3077/4885MAPK1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.