Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309769 | 0.94 | PLG (0.47) | KDM1ACYP1A1CYP1A2ABCC1XDH | |
| SCHEMBL8306911 | 0.94 | PLG (0.47) | KDM1ACYP1A1CYP1A2ABCC1XDH | |
| SCHEMBL8431060 | 0.94 | PLG (0.47) | KDM1ACYP1A1CYP1A2ABCC1XDH | |
| SCHEMBL8309259 | 0.85 | CYP1B1 (0.56) | POLHKDM1ACYP1A1CYP1A2ABCC1 | |
| SCHEMBL8309732 | 0.84 | — | — | |
| SCHEMBL8304422 | 0.83 | CYP1B1 (0.63) | POLHKDM1ACYP1A1CYP1A2ABCC1 | |
| SCHEMBL8309092 | 0.83 | ABCB1 (0.52) | POLHKDM1ACYP1A1CYP1A2ABCC1 | |
| SCHEMBL8431003 | 0.83 | POLB (0.52) | CYP1A2 | |
| SCHEMBL8427267 | 0.82 | KDM4E (0.46) | CYP1A2 | |
| SCHEMBL8306264 | 0.82 | CYP1B1 (0.63) | KDM1ACYP1A1CYP1A2ABCC1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |