⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306911 | 0.85 | PLG (0.47) | — | |
| SCHEMBL8431060 | 0.85 | PLG (0.47) | — | |
| SCHEMBL8309769 | 0.85 | PLG (0.47) | — | |
| SCHEMBL8304672 | 0.84 | POLH (0.47) | — | |
| SCHEMBL8310363 | 0.83 | — | — | |
| SCHEMBL8308176 | 0.82 | AKT1 (0.52) | — | |
| SCHEMBL8309735 | 0.79 | KDM4E (0.39) | — | |
| SCHEMBL8427267 | 0.77 | KDM4E (0.46) | — | |
| SCHEMBL8306325 | 0.75 | AKT1 (0.42) | — | |
| SCHEMBL8431003 | 0.74 | POLB (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |