Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592340 | 0.77 | KDM4E (0.41) | KDM4EGAARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4049174 | 0.77 | TRPV1 (0.47) | KDM4EGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17513265 | 0.76 | CYP1A2 (0.66) | KDM4ETSHRGAANPC1RAB9A | |
| SCHEMBL15410719 | 0.76 | HRH1 (0.42) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6SYK | |
| SCHEMBL19096704 | 0.76 | ASIC3 (0.45) | ALDH1A1SYKAURKBINCENPHRH1 | |
| SCHEMBL9253903 | 0.75 | KDM4E (0.62) | KDM4ETSHRGAANPC1RAB9A | |
| SCHEMBL8304763 | 0.75 | NPC1 (0.42) | KDM4ETSHRNPC1RAB9AMAPT | |
| SCHEMBL792165 | 0.72 | CCR9 (0.45) | KDM4EGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL230753 | 0.72 | HRH1 (0.73) | MAPTSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL29485678 | 0.72 | HRH1 (0.73) | MAPTSMN1; SMN2ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |