Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | HPD | P32754 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215386 | 0.79 | LMNA (0.43) | SMN1; SMN2 | |
| SCHEMBL8303447 | 0.72 | CDC7 (0.39) | PKN1PKN2POLBL3MBTL1 | |
| SCHEMBL1373985 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2PDK1PDK2PDK3PDK4 | |
| SCHEMBL10300849 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL8211915 | 0.70 | SMN1; SMN2 (0.33) | SMN1; SMN2PDE4B | |
| SCHEMBL6214221 | 0.69 | LMNA (0.41) | — | |
| SCHEMBL6322603 | 0.67 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL6216492 | 0.66 | ALDH1A1 (0.33) | SMN1; SMN2POLBL3MBTL1PDE4BKDM4E | |
| SCHEMBL13383596 | 0.66 | MEN1 (0.32) | SMN1; SMN2POLBAPOBEC3AAPOBEC3GTDP1 | |
| SCHEMBL6218280 | 0.66 | LMNA (0.41) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922032-A1 | HERBICIDAL PYRIDINYL AND PYRAZOLYLPHENYL KETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1997046530-A1 | HERBICIDAL PYRIDINYL AND PYRAZOLYLPHENYL KETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-11 | — | — | WO | claimed |
| EP-0922032-A1 | HERBICIDAL PYRIDINYL AND PYRAZOLYLPHENYL KETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997046530-A1 | HERBICIDAL PYRIDINYL AND PYRAZOLYLPHENYL KETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-11 | — | — | WO | disclosed |