Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8301479 | 0.92 | PTGDR2 (0.42) | PTGDR2ADORA1ADORA2AADORA2B | |
| SCHEMBL8322495 | 0.90 | GRM5 (0.34) | — | |
| SCHEMBL8234988 | 0.89 | MAPK14 (0.40) | PTGDR2ADORA1ADORA2AMAPK14RORB | |
| SCHEMBL8292582 | 0.85 | PTGDR2 (0.43) | PTGDR2PGR | |
| SCHEMBL8304828 | 0.85 | PTGDR2 (0.40) | PTGDR2PGRADORA1ADORA2AADORA2B | |
| SCHEMBL8235757 | 0.84 | RORB (0.45) | ADORA1ADORA2AMAPK14RORBKMT2A | |
| SCHEMBL8294963 | 0.84 | PTGDR2 (0.41) | PTGDR2ADORA1ADORA2AADORA2BMAPK14 | |
| SCHEMBL8285415 | 0.84 | PTGDR2 (0.41) | PTGDR2ADORA1ADORA2AADORA2BMAPK14 | |
| SCHEMBL8309906 | 0.83 | PTGDR2 (0.43) | PTGDR2ADORA1ADORA2A | |
| SCHEMBL8284378 | 0.81 | PTGDR2 (0.43) | PTGDR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467381-A1 | SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF FOR TREATING RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2012-06-27 | — | — | EP | disclosed |
| WO-2011020822-A1 | SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF FOR TREATING RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2011-02-24 | — | — | WO | disclosed |