Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236060 | 0.87 | RORB (0.42) | ADORA2AADORA1PDE4APDE4CPDE4D | |
| SCHEMBL8245942 | 0.87 | RORB (0.42) | ADORA2AADORA1PDE4APDE4CPDE4D | |
| SCHEMBL8301479 | 0.87 | PTGDR2 (0.42) | PTGDR2EIF4EADORA2AADORA1PDE4A | |
| SCHEMBL8376658 | 0.87 | PTGDR2 (0.45) | PTGDR2EIF4EADORA2AADORA1XDH | |
| SCHEMBL8309904 | 0.86 | EIF4E (0.46) | PTGDR2EIF4EMCHR1ADORA2AADORA1 | |
| SCHEMBL8304829 | 0.83 | PTGDR2 (0.38) | PTGDR2ADORA2AADORA1 | |
| SCHEMBL8285415 | 0.83 | PTGDR2 (0.41) | PTGDR2ADORA2AADORA1 | |
| SCHEMBL8294963 | 0.83 | PTGDR2 (0.41) | PTGDR2ADORA2AADORA1 | |
| SCHEMBL8236345 | 0.80 | KMO (0.38) | PTGDR2ADORA2AADORA1MDM2CTSA | |
| SCHEMBL8292582 | 0.78 | PTGDR2 (0.43) | PTGDR2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467381-A1 | SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF FOR TREATING RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2012-06-27 | — | — | EP | disclosed |
| WO-2011020822-A1 | SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF FOR TREATING RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2011-02-24 | — | — | WO | disclosed |