Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.64 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 5/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818371 | 0.85 | ALDH1A1 (0.57) | LMNAL3MBTL1KDM4EALDH1A1PKM | |
| SCHEMBL6791588 | 0.83 | AKR1C3 (0.85) | AKR1C3AKR1C1MCOLN3LMNATSHR | |
| SCHEMBL28983197 | 0.79 | AKR1C3 (0.70) | AKR1C3AKR1C1MCOLN3LMNATSHR | |
| SCHEMBL18134604 | 0.79 | MCOLN3 (0.83) | MCOLN3LMNATSHRCTDSP1TDP1 | |
| SCHEMBL7304595 | 0.79 | AKR1C3 (0.82) | AKR1C3AKR1C1MCOLN3LMNATSHR | |
| SCHEMBL14125421 | 0.79 | PKM (0.69) | AKR1C3AKR1C1MCOLN3LMNATSHR | |
| SCHEMBL12939701 | 0.78 | MCOLN3 (0.74) | AKR1C3AKR1C1MCOLN3LMNATSHR | |
| SCHEMBL7303194 | 0.78 | AKR1C3 (1.00) | AKR1C3AKR1C1MCOLN3LMNATSHR | |
| SCHEMBL3212101 | 0.78 | MCOLN3 (0.61) | AKR1C3AKR1C1MCOLN3LMNATSHR | |
| SCHEMBL7329088 | 0.78 | AKR1C3 (0.56) | AKR1C3AKR1C1MCOLN3LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934273-A1 | NEW DERIVATES FROM PIPERIDINE-KETO ACID, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998016512-A1 | NEW DERIVATES FROM PIPERIDINE-KETO ACID, THEIR PREPARATION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-23 | — | — | WO | disclosed |