Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.54 |
| ▸ | CCR4 | P51679 | 5/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2100435 | 0.82 | HCRTR1 (0.65) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 | |
| SCHEMBL30919357 | 0.82 | HCRTR1 (0.65) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 | |
| SCHEMBL2100430 | 0.82 | HCRTR1 (0.65) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 | |
| Hydrochloric Acid SCHEMBL10430459 | 0.81 | HCRTR1 (0.64) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 | |
| SCHEMBL7328060 | 0.80 | GAA (0.53) | ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL7299752 | 0.79 | MCL1 (0.55) | AKR1C3AKR1C1ALDH1A1KDM4E | |
| SCHEMBL3456982 | 0.79 | HCRTR1 (0.64) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 | |
| SCHEMBL2977236 | 0.79 | ALDH1A1 (0.61) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 | |
| SCHEMBL7271544 | 0.79 | HCRTR1 (0.64) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 | |
| SCHEMBL2977241 | 0.79 | ALDH1A1 (0.61) | AKR1C3HCRTR1HCRTR2CCR4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420120-B1 | Optically active benzyl alcohol compound and pharmaceutical composition | HOKURIKU PHARMACEUTICAL (JP) | 1994-08-31 | — | — | EP | claimed |