Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7895923 | 0.82 | ACHE (0.48) | L3MBTL1ATMTDP1ARMRGPRX4 | |
| SCHEMBL7814224 | 0.82 | AR (0.59) | L3MBTL1ATMTDP1ARMRGPRX4 | |
| SCHEMBL7810437 | 0.78 | HAO1 (0.46) | KMT2ALMNAKDM4EMAPTACHE | |
| SCHEMBL7814223 | 0.77 | CNR2 (0.53) | L3MBTL1ATMTDP1KMT2AKDM4E | |
| Methyl Alcohol SCHEMBL28161311 | 0.76 | MAPK1 (0.54) | L3MBTL1KMT2ALMNAMAPTHTT | |
| SCHEMBL5315574 | 0.76 | HAO1 (0.59) | KMT2ALMNAKDM4ESRD5A2SMN1; SMN2 | |
| SCHEMBL7814092 | 0.75 | ACHE (0.47) | MRGPRX4KMT2ALMNAKDM4EMAPT | |
| SCHEMBL7897148 | 0.75 | AR (0.48) | L3MBTL1TDP1ARMRGPRX4KMT2A | |
| SCHEMBL11820078 | 0.75 | MRGPRX4 (0.51) | ARMRGPRX4LMNAHTTSMN1; SMN2 | |
| SCHEMBL8304985 | 0.74 | LMNA (0.50) | L3MBTL1ATMTDP1LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891345-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997037984-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1997-10-16 | — | — | WO | disclosed |