Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | LDHB | P07195 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510579 | 0.87 | TSHR (0.56) | LMNATBXAS1ALDH1A1SRD5A2LDHA | |
| SCHEMBL13862516 | 0.85 | L3MBTL1 (0.53) | LMNAATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7895926 | 0.81 | ACHE (0.51) | LMNAATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL12337417 | 0.79 | ALDH1A1 (0.61) | LMNAATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7810440 | 0.78 | ACHE (0.52) | LMNAATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL24590014 | 0.78 | SMN1; SMN2 (0.50) | LMNAATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7814226 | 0.77 | POLB (0.59) | LMNAATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL10007010 | 0.77 | SMN1; SMN2 (0.71) | LMNAATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL166495 | 0.77 | SMN1; SMN2 (0.71) | LMNAATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL4004691 | 0.77 | LMNA (0.67) | LMNAATMTDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891345-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997037984-A1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1997-10-16 | — | — | WO | disclosed |