Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309333 | 0.89 | CYP1B1 (0.57) | AKT1HDAC6PTPN1CYP1B1FLT3 | |
| SCHEMBL8304148 | 0.85 | DYRK1A (0.49) | AKT1CYP1B1CYP1A1CYP1A2HPGD | |
| SCHEMBL8305265 | 0.85 | CYP1B1 (0.65) | AKT1PTGESALOX5ABCG2HDAC6 | |
| SCHEMBL8308046 | 0.84 | MAOB (0.52) | ABCG2HDAC6CYP1B1FLT3CYP1A1 | |
| SCHEMBL30598448 | 0.84 | ALDH1A1 (0.43) | PTPN1CYP1B1CYP1A1CYP1A2HPGD | |
| SCHEMBL4574807 | 0.84 | ALDH1A1 (0.43) | PTPN1CYP1B1CYP1A1CYP1A2HPGD | |
| SCHEMBL8308179 | 0.84 | HDAC6 (0.51) | AKT1PTGESALOX5HDAC6CYP1B1 | |
| SCHEMBL8305275 | 0.83 | AKT1 (0.42) | AKT1PTGESALOX5ABCG2HDAC6 | |
| SCHEMBL8429592 | 0.82 | XDH (0.52) | ABCG2HDAC6CYP1B1FLT3CYP1A1 | |
| SCHEMBL8305036 | 0.81 | MAPT (0.59) | ABCG2HDAC6CYP1B1CYP1A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |