Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 8/20 | 0.36 |
| ▸ | ACACA | Q13085 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305075 | 1.00 | MET (0.36) | METALDH1A1ACACBACACASMN1; SMN2 | |
| SCHEMBL8307070 | 0.85 | NNMT (0.46) | METSMN1; SMN2LMNAPTBP1PDE3B | |
| SCHEMBL8307069 | 0.85 | NNMT (0.46) | METSMN1; SMN2LMNAPTBP1PDE3B | |
| SCHEMBL8309510 | 0.83 | MAPT (0.51) | METACACBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8309507 | 0.83 | MAPT (0.51) | METACACBSMN1; SMN2LMNAPTBP1 | |
| SCHEMBL8687164 | 0.79 | ALDH1A1 (0.38) | ALDH1A1ACACBACACAPDE10AMAPT | |
| SCHEMBL8304738 | 0.78 | ALDH1A1 (0.42) | ALDH1A1ACACBACACAPDE10AMAPT | |
| SCHEMBL29483234 | 0.78 | ALDH1A1 (0.42) | ALDH1A1ACACBACACAPDE10AMAPT | |
| SCHEMBL8309324 | 0.76 | MEN1 (0.41) | ACACBACACAL3MBTL1 | |
| SCHEMBL8304541 | 0.73 | PPARG (0.54) | METALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |