Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305218 | 1.00 | PPARG (0.46) | PPARGCYP2C9PPARACYP3A4KCNH2 | |
| SCHEMBL8306456 | 0.86 | PPARG (0.49) | PPARGCYP2C9FFAR1RARGRXRA | |
| SCHEMBL8306453 | 0.86 | PPARG (0.49) | PPARGCYP2C9FFAR1RARGRXRA | |
| SCHEMBL8305011 | 0.85 | PPARG (0.47) | PPARGCYP2C9PPARACYP3A4KCNH2 | |
| SCHEMBL8307060 | 0.85 | PPARG (0.55) | PPARGFFAR1MAPT | |
| SCHEMBL8307062 | 0.85 | PPARG (0.55) | PPARGFFAR1MAPT | |
| SCHEMBL8310404 | 0.85 | PPARG (0.44) | PPARGPPARAFFAR1RARGRXRA | |
| SCHEMBL8310405 | 0.85 | PPARG (0.44) | PPARGPPARAFFAR1RARGRXRA | |
| SCHEMBL8390605 | 0.83 | PPARG (0.66) | PPARGPPARAFFAR1RARGRXRA | |
| SCHEMBL8390608 | 0.83 | PPARG (0.66) | PPARGPPARAFFAR1RARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |