Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 5/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | FECH | P22830 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574499 | 0.81 | POLB (0.36) | ATMCHRNB2CHRNA4 | |
| SCHEMBL7897890 | 0.80 | BCAT1 (0.49) | MEN1KMT2AOXTRGRIN1GRIN2B | |
| SCHEMBL7896541 | 0.78 | MTOR (0.40) | PTGS1PTGS2MEN1KMT2AOXTR | |
| SCHEMBL7833292 | 0.72 | NOTUM (0.48) | ATMMEN1KMT2AGSK3AMAPT | |
| SCHEMBL30615552 | 0.70 | MEN1 (0.47) | MEN1KMT2AOXTRRIOK2AVPR1A | |
| SCHEMBL10143726 | 0.70 | MEN1 (0.47) | MEN1KMT2AOXTRRIOK2AVPR1A | |
| SCHEMBL23565505 | 0.69 | CYP2C9 (0.58) | MEN1KMT2AOXTRCHRNB2CHRNA4 | |
| SCHEMBL21463368 | 0.68 | DAO (0.46) | MEN1KMT2AOXTRCHRNB2CHRNA4 | |
| SCHEMBL30615678 | 0.68 | DAO (0.46) | MEN1KMT2AOXTRRIOK2AVPR1A | |
| SCHEMBL30615377 | 0.68 | DAO (0.46) | MEN1KMT2AOXTRCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946544-A1 | HETEROCYCLYLURACIL | BAYER AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027082-A1 | HETEROCYCLYLURACIL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |