SCHEMBL7897890

SCHEMBL7897890

COc1ccc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)cn1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 14/20 0.49
BCAT2 O15382 12/20 0.49
OXTR P30559 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7898956 0.81 BCAT1 (0.46) BCAT1BCAT2ALDH1A1CYP2C9CYP2C19
SCHEMBL7556878 0.80 ALDH1A1 (0.55) BCAT1BCAT2KMT2AALDH1A1SMN1; SMN2
SCHEMBL8305252 0.80 ATM (0.42) OXTRMEN1KMT2AGRIN1GRIN2B
SCHEMBL11781513 0.76 ALDH1A1 (0.56) BCAT1BCAT2MEN1KMT2AALDH1A1
SCHEMBL7896541 0.75 MTOR (0.40) OXTRMEN1KMT2A
SCHEMBL7038819 0.72 BCAT1 (0.72) BCAT1BCAT2
SCHEMBL11785182 0.72 ALDH1A1 (0.55) BCAT1BCAT2ALDH1A1CYP2C9CYP2C19
SCHEMBL8697055 0.71 SMN1; SMN2 (0.48) BCAT1BCAT2MEN1KMT2AALDH1A1
SCHEMBL30615552 0.70 MEN1 (0.47) OXTRMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL10143726 0.70 MEN1 (0.47) OXTRMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187716-B1 PREPARING THESE SUBSTANCES AND THEIR USE AS HERBICIDES. BAYER AKTIENGESELLSCHAFT (DE) 2001-02-13 US disclosed