Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982859 | 0.72 | TRPA1 (0.44) | ALDH1A1MAPTKDM4EMEN1POLB | |
| SCHEMBL4473038 | 0.72 | TDP2 (0.46) | PTGS1PTGS2ALDH1A1MAPTLMNA | |
| SCHEMBL4447138 | 0.71 | KMT2A (0.41) | PTGS1PTGS2ADORA2AALDH1A1MAPT | |
| SCHEMBL8337482 | 0.71 | MAPT (0.36) | PTGS1PTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL30159162 | 0.71 | FABP3 (0.41) | PTGS1PTGS2ADORA2AALDH1A1MAPT | |
| SCHEMBL27471884 | 0.71 | TSHR (0.33) | ALDH1A1RAB9ASMN1; SMN2CYP1A2CYP2A6 | |
| SCHEMBL22391489 | 0.70 | MAPT (0.48) | PTGS1PTGS2ALDH1A1MAPTRAB9A | |
| SCHEMBL23106363 | 0.69 | ADORA2A (0.40) | PTGS2ADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL20344255 | 0.69 | HDAC1 (0.41) | ADORA2AADORA1ALDH1A1MAPTKDM4E | |
| SCHEMBL11226020 | 0.69 | KMT2A (0.36) | PTGS1PTGS2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914317-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998052926-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-11-26 | — | — | WO | disclosed |