Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714749 | 0.86 | ESR2 (0.44) | ALOX5BACE1ESR2PDE4BPDE4A | |
| SCHEMBL30335040 | 0.86 | ALOX5 (0.44) | TRPA1ATMALOX5BACE1ESR2 | |
| SCHEMBL4275553 | 0.86 | ALOX5 (0.44) | TRPA1ATMALOX5BACE1ESR2 | |
| SCHEMBL27708307 | 0.84 | ESR2 (0.43) | ALOX5BACE1ESR2PDE4BPDE4A | |
| SCHEMBL27957735 | 0.84 | PDE4B (0.44) | TRPA1ALOX5BACE1ESR2PDE4B | |
| SCHEMBL27491844 | 0.84 | TRPA1 (0.43) | TRPA1ATMALOX5BACE1ESR2 | |
| SCHEMBL6227967 | 0.83 | TRPA1 (0.48) | TRPA1ATMESR2ESR1KDM4E | |
| SCHEMBL28155065 | 0.81 | MAPT (0.42) | ALOX5ESR2ESR1KDM4EGAA | |
| SCHEMBL27530617 | 0.81 | TTR (0.43) | ALOX5BACE1ESR2PDE4BPDE4A | |
| SCHEMBL11649175 | 0.81 | HPGD (0.50) | TRPA1ATMALOX5BACE1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957152-A | Synthetic method of benzoxazole compound | 湖南第一师范学院 | 2022-08-30 | — | — | CN | claimed |
| CN-114957152-B | Synthesis method of benzoxazole compound | 湖南第一师范学院 | 2023-11-17 | — | — | CN | disclosed |
| CN-114957152-A | Synthetic method of benzoxazole compound | 湖南第一师范学院 | 2022-08-30 | — | — | CN | disclosed |
| CN-114040907-A | Method for producing diphenylsulfone compound | 小西化学工业株式会社 | 2022-02-11 | — | — | CN | disclosed |
| CN-111607244-B | Natural polyphenol cross-linked palm oil-based resin-based bamboo fiber reinforced composite material and preparation method thereof | 福建农林大学 | 2022-01-07 | — | — | CN | disclosed |
| CN-112679635-A | Preparation method of supported metallocene catalyst and catalyst prepared by same | 中国石油化工股份有限公司 | 2021-04-20 | — | — | CN | disclosed |
| EP-2275405-B1 | PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE | ASAHI CHEMICAL IND (JP) | 2019-04-24 | — | — | EP | disclosed |
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| EP-2792673-B1 | Carbamic acid ester derivatives for the production of isocyanate and aromatic hydroxy compounds | ASAHI CHEMICAL IND (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9637445-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| US-7615650-B2 | Process for producing chroman compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-11-10 | — | — | US | disclosed |
| WO-2009108704-A1 | O-ALKYLATED PI-3 KINASE INHIBITOR PRODRUG COMBINATION | SEMAFORE PHARMACEUTICALS, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| US-20080188423-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SIGNALRX PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188423-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SIGNALRX PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-7396828-B2 | PI-3 kinase inhibitor prodrugs | SEMAFORE PHARMACEUTICALS, INC. (US) | 2008-07-08 | — | — | US | disclosed |
| US-7396828-B2 | PI-3 kinase inhibitor prodrugs | SEMAFORE PHARMACEUTICALS, INC. (US) | 2008-07-08 | — | — | US | disclosed |
| US-20070179304-A1 | Process for producing chroman compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1710239-A1 | PROCESS FOR PRODUCING CHROMAN COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-10-11 | — | — | EP | disclosed |
| WO-2004089925-A1 | PI-3 KINASE INHIBITOR PRODRUGS | SEMAFORE PHARMACEUTICALS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188423-A1 | PI-3 KINASE INHIBITOR PRODRUGS | PI4KA, PI4KB, PI4K2B | TRPA1 4096/4885ATM 436/4885ALOX5 3296/4885 |
| US-20070179304-A1 | Process for producing chroman compound | TAF9, TAF1, CHD1 | TRPA1 1335/4885ATM 3330/4885ALOX5 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.