Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305543 | 1.00 | GABRA1 (0.46) | GABRA1GABRB2KMT2AMAPTGAA | |
| SCHEMBL8686060 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2KMT2AMAPTNPC1 | |
| SCHEMBL5610797 | 0.76 | LMNA (0.56) | MAPTHTTL3MBTL1NPC1RAB9A | |
| SCHEMBL5610798 | 0.76 | LMNA (0.56) | MAPTHTTL3MBTL1NPC1RAB9A | |
| SCHEMBL8309932 | 0.76 | PPARA (0.48) | HTTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8309933 | 0.76 | PPARA (0.48) | HTTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5609899 | 0.75 | LMNA (0.65) | MAPTHTTL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL5609892 | 0.75 | LMNA (0.65) | MAPTHTTL3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL8443076 | 0.74 | LMNA (0.42) | HTTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5609817 | 0.74 | PPARG (0.50) | MAPTHTTL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |