Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | SI | P14410 | 3/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300662 | 0.87 | MAPT (0.38) | MAPTKDM4EALDH1A1MAPK1GAA | |
| SCHEMBL8302118 | 0.86 | DPP4 (0.35) | ALDH1A1POLB | |
| SCHEMBL8301544 | 0.85 | GHSR (0.34) | — | |
| SCHEMBL8301326 | 0.85 | CA12 (0.35) | ALDH1A1CA12CA9RAB9ASMN1; SMN2 | |
| SCHEMBL8301349 | 0.84 | MEN1 (0.34) | MAPTKDM4EALDH1A1MAPK1GAA | |
| SCHEMBL8300843 | 0.84 | GSK3B (0.34) | POLB | |
| SCHEMBL8306931 | 0.82 | HEXA (0.34) | MAPTKDM4EALDH1A1POLB | |
| SCHEMBL8300550 | 0.80 | MAPT (0.37) | MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8303758 | 0.79 | HEXA (0.35) | POLBADORA3ADORA1 | |
| SCHEMBL7951460 | 0.76 | KAT6A (0.33) | MAPTKDM4ECHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914317-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998052926-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-11-26 | — | — | WO | disclosed |