Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300662 | 0.90 | MAPT (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8303758 | 0.89 | HEXA (0.35) | PIN1GRK6SLC9A1 | |
| SCHEMBL8306715 | 0.85 | CRHR1 (0.36) | MAPTROCK2KDM4ETP53ROCK1 | |
| SCHEMBL8302118 | 0.83 | DPP4 (0.35) | ALDH1A1 | |
| SCHEMBL8301326 | 0.82 | CA12 (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8301544 | 0.82 | GHSR (0.34) | — | |
| SCHEMBL8301349 | 0.81 | MEN1 (0.34) | MAPTSMN1; SMN2KDM4EALDH1A1TP53 | |
| SCHEMBL8300843 | 0.81 | GSK3B (0.34) | GRK6 | |
| SCHEMBL8305579 | 0.80 | MAPT (0.33) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8306931 | 0.79 | HEXA (0.34) | MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914317-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998052926-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-11-26 | — | — | WO | disclosed |