SCHEMBL8305745

SCHEMBL8305745

Cc1noc(Cl)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 1/20 0.38
HCAR2 Q8TDS4 1/20 0.36
GAA P10253 4/20 0.36
POLB P06746 3/20 0.36
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 1/20 0.35
AGTR1 P30556 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
FTO Q9C0B1 1/20 0.34
USP2 O75604 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223413 0.77 GAA (0.49) ALDH1A1TSHRGAALMNAMAPT
Hydrochloric Acid SCHEMBL19119186 0.76 GAA (0.47) ALDH1A1TSHRGAALMNAMAPT
SCHEMBL20027632 0.75 ALDH1A1 (0.51) ALDH1A1HPGDTSHRSMN1; SMN2GAA
SCHEMBL938250 0.74 CYP1A2 (0.49) ALDH1A1TSHRSMN1; SMN2HCAR2GAA
SCHEMBL21806565 0.74 HCAR2 (0.36) ALDH1A1TSHRMAPK1HCAR2GAA
SCHEMBL9199700 0.72 POLB (0.45) ALDH1A1HPGDTSHRHCAR2GAA
SCHEMBL9446185 0.72 POLB (0.42) ALDH1A1HPGDTSHRSMN1; SMN2MAPK1
SCHEMBL4336589 0.71 MAPT (0.51) ALDH1A1SMN1; SMN2POLBLMNAMAPT
SCHEMBL8303828 0.71 ALDH1A1 (0.44) ALDH1A1HPGDTSHRSMN1; SMN2MAPK1
SCHEMBL354660 0.71 TSHR (0.39) ALDH1A1HPGDTSHRHCAR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688741-A1 COMPOUNDS FOR TREATING FIBROTIC DISEASES Meta-Immune, Inc. (KR) 2026-02-11 EP disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
WO-2024249867-A1 COMPOUNDS FOR TREATING FIBROTIC DISEASES AM SCIENCES (KR) 2024-12-05 WO disclosed
CN-110023304-A Calpain regulator and its therapeutical uses 布莱德治疗公司 2019-07-16 CN disclosed
EP-1937682-B1 MET KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2015-08-12 EP disclosed
US-7547782-B2 Met kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2009-06-16 US disclosed
US-7547782-B2 Met kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2009-06-16 US disclosed
WO-2007041379-A1 MET KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-04-12 WO disclosed
US-20070078140-A1 MET kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY 2007-04-05 US disclosed
US-20070078140-A1 MET kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY 2007-04-05 US disclosed
CN-1058490-C Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 2000-11-15 CN disclosed
EP-0695748-B1 Tetrazolinone herbicides BAYER AGROCHEM KK (JP) 1999-05-06 EP disclosed
US-5589439-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1996-12-31 US disclosed
CN-1122333-A Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 1996-05-15 CN disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078140-A1 MET kinase inhibitors MET, ABL1, ERBB2 ALDH1A1 1225/4885HPGD 4066/4885TSHR 1424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.