SCHEMBL9199700

SCHEMBL9199700

Cc1noc(C(N)=O)c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.45
KMT2A Q03164 2/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 1/20 0.39
HCAR2 Q8TDS4 1/20 0.35
KDM4E B2RXH2 2/20 0.35
CYP1A2 P05177 2/20 0.34
GRIA1 P42261 1/20 0.34
GRIA3 P42263 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1667303 0.78 POLB (0.40) POLBKMT2AGAAMEN1KDM4E
SCHEMBL9446211 0.78 ALDH1A1 (0.49) POLBKMT2AGAAMEN1KDM4E
SCHEMBL938250 0.77 CYP1A2 (0.49) POLBKMT2AGAAMEN1HCAR2
SCHEMBL3535408 0.76 POLB (0.39) POLBKMT2AGAAMEN1KDM4E
SCHEMBL223413 0.76 GAA (0.49) KMT2AGAAMEN1KDM4EALDH1A1
SCHEMBL3625472 0.75 RAB9A (0.50) POLBKMT2AGAAMEN1KDM4E
SCHEMBL9446185 0.75 POLB (0.42) POLBGAAHCAR2CYP1A2GRIA1
Hydrochloric Acid SCHEMBL19119186 0.74 GAA (0.47) KMT2AGAAMEN1KDM4EALDH1A1
SCHEMBL352276 0.74 GAA (0.53) POLBKMT2AGAAMEN1KDM4E
SCHEMBL18650792 0.73 POLB (0.44) POLBKMT2AGAAMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0418667-B1 Carboxylic acid amides BASF AG (DE) 1995-08-16 EP disclosed
US-5205854-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1993-04-27 US disclosed
US-5201932-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed
EP-0337263-B1 ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES BASF Aktiengesellschaft (DE) 1993-03-17 EP disclosed
US-5080708-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1992-01-14 US disclosed
EP-0337263-A2 Isoxazol(isothiazols)-5-carboxamides BASF Aktiengesellschaft (DE) 1989-10-18 EP disclosed