Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.49 |
| ▸ | DRD3 | P35462 | 18/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151335 | 0.89 | DRD2 (0.44) | DRD2DRD3KCNH2 | |
| SCHEMBL8149406 | 0.78 | DRD2 (0.61) | DRD2DRD3KCNH2DRD4HTR2A | |
| SCHEMBL8156167 | 0.76 | DRD2 (0.55) | DRD2DRD3KCNH2DRD4HTR2A | |
| SCHEMBL8142915 | 0.74 | DRD2 (0.57) | DRD2DRD3KCNH2DRD4HTR2A | |
| SCHEMBL8156679 | 0.72 | DRD2 (0.55) | DRD2DRD3KCNH2DRD4HTR2A | |
| SCHEMBL8148960 | 0.70 | DRD2 (0.55) | DRD2DRD3KCNH2DRD4HTR2A | |
| SCHEMBL8150800 | 0.70 | HTR1A (0.57) | — | |
| SCHEMBL8142907 | 0.70 | DRD2 (0.55) | DRD2DRD3 | |
| SCHEMBL8155543 | 0.69 | DRD2 (0.54) | DRD2DRD3KCNH2DRD4HTR2A | |
| SCHEMBL11036699 | 0.69 | DRD2 (0.91) | DRD2DRD3KCNH2DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673375-B1 | FUSED BENZO COMPOUNDS | LUNDBECK & CO AS H (DK) | 1999-02-24 | — | — | EP | claimed |