Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356782 | 0.94 | GRIA1 (0.48) | MMP8KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7358942 | 0.91 | KMT2A (0.53) | MMP8KMT2AL3MBTL1 | |
| SCHEMBL7362788 | 0.89 | MMP8 (0.48) | MMP8KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7363911 | 0.88 | CHRNA1 (0.58) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7356539 | 0.87 | L3MBTL1 (0.47) | KMT2AGRIA1L3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL8875868 | 0.86 | PLG (0.53) | KMT2AGRIA1L3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL7356791 | 0.86 | GRIA1 (0.47) | MMP8KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7362797 | 0.85 | SRC (0.47) | MMP8KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7359233 | 0.85 | BRS3 (0.51) | KMT2ACNR1NPC1RAB9A | |
| SCHEMBL7362904 | 0.84 | LAP3 (0.51) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |