Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29593007 | 1.00 | L3MBTL1 (0.55) | L3MBTL1MAPTTDP1HPGDTSHR | |
| SCHEMBL11773610 | 0.90 | L3MBTL1 (0.54) | L3MBTL1MAPTTDP1HPGDTSHR | |
| SCHEMBL668412 | 0.86 | L3MBTL1 (0.52) | L3MBTL1MAPTTDP1HPGDTSHR | |
| SCHEMBL30741241 | 0.84 | CA12 (0.48) | L3MBTL1MAPTTDP1CYP1A2SMN1; SMN2 | |
| SCHEMBL3185351 | 0.84 | CA12 (0.48) | L3MBTL1MAPTTDP1CYP1A2SMN1; SMN2 | |
| SCHEMBL30741239 | 0.84 | CA12 (0.48) | L3MBTL1MAPTTDP1CYP1A2SMN1; SMN2 | |
| SCHEMBL9819251 | 0.83 | ALDH1A1 (0.46) | L3MBTL1MAPTTDP1TSHRCYP1A2 | |
| SCHEMBL11748056 | 0.82 | L3MBTL1 (0.53) | L3MBTL1MAPTTDP1HPGDTSHR | |
| SCHEMBL21736857 | 0.82 | MRGPRX4 (0.47) | L3MBTL1MAPTTDP1HPGDTSHR | |
| SCHEMBL14804184 | 0.81 | L3MBTL1 (0.68) | L3MBTL1MAPTTDP1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502556-B | Biphenyl fluoro double bond derivative, preparation method thereof and application thereof in pharmacy | 上海和誉生物医药科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-115605475-A | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-114502556-A | Biphenyl fluoro double bond derivative and preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-9815811-B2 | Inhibitors of the kynurenine pathway | CURADEV PHARMA, PVT. LTD. (IN) | 2017-11-14 | — | — | US | disclosed |
| CN-105008375-B | Tetrahydroimidazo [1,5-d ] [1,4] oxazepine derivatives | 卫材R&D管理有限公司 | 2016-12-28 | — | — | CN | disclosed |
| US-20160046596-A1 | INHIBITORS OF THE KYNURENINE PATHWAY | CURADEV PHARMA PRIVATE LTD. (IN) | 2016-02-18 | — | — | US | disclosed |
| CN-105008375-A | Tetrahydroimidazo [1,5-d ] [1,4] oxazepine derivatives | WEI CAIR | 2015-10-28 | — | — | CN | disclosed |
| CN-102361837-B | Process for producing conjugated aromatic compound | SUMITOMO CHEMICAL CO | 2014-07-02 | — | — | CN | disclosed |
| US-8765764-B2 | 2-acylaminothiazole derivative or salt thereof | ASTELLAS PHARMA, INC. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20130079351-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA, INC. (JP) | 2013-03-28 | — | — | US | disclosed |
| WO-1998003505-A2 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |
| EP-0403026-B1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DOWELANCO (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5158597-A | Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5071465-A | Preemergence; postemergence | THE DOW CHEMICAL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| US-4999448-A | ALKYLATION WITH PHENYLTHIOMETHYL LITHIUM COMPOUND, CYCLIZATION, INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| US-4979978-A | Herbicidal 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0403026-A1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DowElanco (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-3944389-A | Detection of chloromethyl methyl ether or bis-chloro-methyl ether | THE DOW CHEMICAL COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
| US-3934981-A | Apparatus for detection of chloromethyl methyl ether or bis-chloromethyl ether | THE DOW CHEMICAL COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079351-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | MPL, JAK2, ABL1 | L3MBTL1 1136/4885MAPT 4550/4885TDP1 4760/4885 |
| US-20160046596-A1 | INHIBITORS OF THE KYNURENINE PATHWAY | IDO1, KYNU, IDO2 | L3MBTL1 3366/4885MAPT 3218/4885TDP1 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.