Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578752 | 0.83 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL7494328 | 0.80 | DRD2 (0.42) | DRD2DRD3HTR2A | |
| SCHEMBL15688078 | 0.80 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL12696027 | 0.80 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| SCHEMBL590892 | 0.80 | HTR1A (0.40) | HTR1ADRD2DRD3HTR2A | |
| SCHEMBL2406116 | 0.80 | HTR1A (0.46) | HTR1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL15688231 | 0.78 | HTR1A (0.45) | HTR1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL15687944 | 0.78 | HTR1A (0.45) | HTR1ADRD2DRD3 | |
| SCHEMBL29045090 | 0.78 | HTR1A (0.47) | HTR1ADRD2DRD3 | |
| SCHEMBL8306011 | 0.77 | HTR1A (0.38) | HTR1ADRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717738-B1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | UPJOHN CO (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5880118-A | Substituted oxazine and thiazine oxazolidinone antimicrobials | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| US-5688792-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0717738-A1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007271-A1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | THE UPJOHN COMPANY (US) | 1995-03-16 | — | — | WO | disclosed |