Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306101 | 0.83 | HTR1A (0.42) | HTR1ADRD2DRD3 | |
| SCHEMBL590892 | 0.80 | HTR1A (0.40) | HTR1ADRD2DRD3 | |
| SCHEMBL15793169 | 0.80 | HTR1A (0.49) | HTR1ADRD2DRD3 | |
| SCHEMBL8306011 | 0.77 | HTR1A (0.38) | HTR1ADRD2DRD3 | |
| SCHEMBL27885240 | 0.74 | DRD2 (0.54) | HTR1ADRD2DRD3 | |
| SCHEMBL13701281 | 0.74 | KDM1A (0.33) | — | |
| SCHEMBL6225983 | 0.74 | DRD2 (0.53) | HTR1ADRD2DRD3 | |
| SCHEMBL8775830 | 0.73 | DRD2 (0.56) | HTR1ADRD2DRD3 | |
| SCHEMBL9094897 | 0.72 | DRD2 (0.39) | DRD2 | |
| SCHEMBL503067 | 0.72 | DRD2 (0.54) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556071-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | University Health Network (CA) | 2013-02-13 | — | — | EP | disclosed |
| EP-2417127-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | University Health Network (CA) | 2012-02-15 | — | — | EP | disclosed |
| WO-2011123946-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |
| WO-2010115279-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2010-10-14 | — | — | WO | disclosed |