Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FABP6 | P51161 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269433 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL833047 | 0.84 | CD44 (0.42) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL8269424 | 0.80 | GRIA1 (0.39) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL8292367 | 0.79 | NNMT (0.37) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL8291075 | 0.79 | KDM4E (0.38) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL14490504 | 0.79 | L3MBTL1 (0.42) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL377405 | 0.75 | MAPT (0.53) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL11704181 | 0.70 | MAPT (0.57) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL12665748 | 0.67 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTHSD17B10TLR4 | |
| SCHEMBL7377529 | 0.67 | KDM4E (0.53) | ALDH1A1KDM4EMAPTHSD17B10TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |
| US-4242495-A | COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-12-30 | — | — | US | disclosed |