SCHEMBL1822840

SCHEMBL1822840

Cc1cc2c(s1)Cc1sc(C)cc1-2

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.39
MEN1 O00255 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17339888 0.89 ALDH1A1 (0.34) PNMTMEN1TSHRCYP2C19RAB9A
SCHEMBL2915061 0.80 PNMT (0.34) PNMTMEN1TSHRCYP2C19RAB9A
SCHEMBL4479100 0.79 CHEK1 (0.42) PNMTTSHRCYP2C19RAB9AALDH1A1
SCHEMBL13600309 0.77 TDP1 (0.35) PNMT
SCHEMBL13600312 0.77 MEN1 (0.30) PNMTMEN1KMT2AALDH1A1
SCHEMBL13183624 0.77 METAP1 (0.43) PNMTMEN1RAB9AKMT2AALDH1A1
SCHEMBL14864794 0.77 ADORA1 (0.50) PNMTMEN1RAB9AKMT2AALDH1A1
SCHEMBL4500371 0.77 PNMT (0.40) PNMTMEN1TSHRCYP2C19RAB9A
SCHEMBL13827392 0.76 PNMT (0.47) PNMTMEN1TSHRCYP2C19RAB9A
SCHEMBL13600316 0.74 CCR1 (0.33) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622948-B1 PROCESS FOR POLYMERIZING 1-BUTENE BASELL POLYOLEFINE GMBH (DE) 2019-11-20 EP disclosed
US-9570688-B2 Semiconductor materials prepared from bridged bithiazole copolymers BASF SE (DE) 2017-02-14 US disclosed
US-20130144065-A1 SEMICONDUCTOR MATERIALS PREPARED FROM BRIDGED BITHIAZOLE COPOLYMERS POLYERA CORPORATION (US) 2013-06-06 US disclosed
US-8431680-B2 Semiconductor materials based on thienothiophene-2,5-dione oligomers and polymers BASF SE (DE) 2013-04-30 US disclosed
US-20120296058-A1 SEMICONDUCTOR MATERIALS BASED ON THIENOTHIOPHENE-2,5-DIONE OLIGOMERS AND POLYMERS BASF SE (DE) 2012-11-22 US disclosed
WO-2012146574-A1 SEMICONDUCTOR MATERIALS BASED ON DIKETOPIPERIDINOPIPERIDINE COPOLYMERS BASF SE (DE) 2012-11-01 WO disclosed
US-8003743-B2 Low elastic modulus, high molecular weight; high yield; polymerization catalysts such as dimethylsilanediyl{5-(1,1,3,3,6-pentamethyl-1,2,3,5-tetrahydroindacenyl)-7-(2,5-dimethyl-cyclopenta[1,2-b:4,3-b']-dithiophene)}zirconium dichloride Basell Poliolefine Italia, s.r.l. (IT) 2011-08-23 US disclosed
EP-1854804-B1 Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers BASELL POLYOLEFINE GMBH (DE) 2011-05-04 EP disclosed
EP-1854804-B1 Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers BASELL POLYOLEFINE GMBH (DE) 2011-05-04 EP disclosed
US-20100249346-A1 METALLOCENE COMPOUNDS BASED ON ETHANEDIYL-BRIDGED INDENE AND CYCLOPENTADITHIOPHENE LIGANDS BASELL POLYOLEFINE GMBH (DE) 2010-09-30 US disclosed
US-20020198339-A1 Process for the preparation of ethylene polymers EQUISTAR CHEMICALS, LP 2002-12-26 US disclosed
US-20020147286-A1 Process for producing substantially amorphous propylene-based polymers EQUISTAR CHEMICALS, LP 2002-10-10 US disclosed
EP-1226193-A2 PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS Basell Technology Company B.V. (NL) 2002-07-31 EP disclosed
EP-1187877-A1 THERMOPLASTIC COMPOSITIONS OF ISOTACTIC PROPYLENE POLYMERS AND FLEXIBLE PROPYLENE POLYMERS HAVING REDUCED ISOTACTICITY AND A PROCESS FOR THE PREPARATION THEREOF Basell Technology Company B.V. (NL) 2002-03-20 EP disclosed
EP-1159310-A1 PROCESS FOR PRODUCING SUBSTANTIALLY AMORPHOUS PROPYLENE-BASED POLYMERS Basell Technology Company B.V. (NL) 2001-12-05 EP disclosed
EP-1157027-A1 HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS Basell Technology Company B.V. (NL) 2001-11-28 EP disclosed
WO-2001070878-A1 THERMOPLASTIC COMPOSITIONS OF ISOTACTIC PROPYLENE POLYMERS AND FLEXIBLE PROPYLENE POLYMERS HAVING REDUCED ISOTACTICITY AND A PROCESS FOR THE PREPARATION THEREOF BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-09-27 WO disclosed
WO-2001053360-A1 PROCESS FOR PRODUCING SUBSTANTIALLY AMORPHOUS PROPYLENE-BASED POLYMERS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-07-26 WO disclosed
WO-2001047939-A1 HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-07-05 WO disclosed
WO-2001048039-A2 PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249346-A1 METALLOCENE COMPOUNDS BASED ON ETHANEDIYL-BRIDGED INDENE AND CYCLOPENTADITHIOPHENE LIGANDS CHRM1, CCNT1, CYC1 PNMT 807/4885MEN1 142/4885TSHR 829/4885
US-20020147286-A1 Process for producing substantially amorphous propylene-based polymers GRB7, CHRM1, CPNE4 PNMT 1894/4885MEN1 2468/4885TSHR 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.