Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 1.00 |
| ▸ | CTSL | P07711 | 9/20 | 1.00 |
| ▸ | CTSK | P43235 | 9/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260512 | 0.89 | CTSS (0.81) | CTSSCTSLCTSK | |
| SCHEMBL4952069 | 0.89 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5260375 | 0.84 | CTSS (0.90) | CTSSCTSLCTSK | |
| SCHEMBL4952011 | 0.84 | CTSS (0.82) | CTSSCTSLCTSK | |
| SCHEMBL5257836 | 0.82 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5262550 | 0.82 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL5262717 | 0.82 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5262713 | 0.82 | CTSS (0.84) | CTSSCTSLCTSK | |
| SCHEMBL5260821 | 0.81 | CTSS (0.67) | CTSSCTSLCTSK | |
| SCHEMBL4269451 | 0.81 | CTSS (0.67) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037835-A1 | Pharmaceutical composition comprising a cathepsin s inhibitor and an opioid | NOVARTIS AG (CH) | 2007-02-15 | — | — | US | disclosed |
| US-20070037835-A1 | Pharmaceutical composition comprising a cathepsin s inhibitor and an opioid | NOVARTIS AG (CH) | 2007-02-15 | — | — | US | disclosed |
| WO-2004096227-A1 | PHARMACEUTICAL COMPOSITON COMPRISING A CATHEPSIN S INHIBITOR AND AN OPIOID | NOVARTIS AG (CH) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037835-A1 | Pharmaceutical composition comprising a cathepsin s inhibitor and an opioid | CTSS, CTSB, CTSG | CTSS 1/4885CTSL 10/4885CTSK 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.