Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309140 | 0.91 | TBXAS1 (0.75) | TBXAS1 | |
| SCHEMBL8308007 | 0.85 | TBXAS1 (0.70) | TBXAS1KDM4E | |
| SCHEMBL8310272 | 0.83 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8305539 | 0.83 | TBXAS1 (0.77) | TBXAS1 | |
| SCHEMBL8308584 | 0.82 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8309401 | 0.79 | TBXAS1 (0.52) | TBXAS1 | |
| SCHEMBL8310499 | 0.78 | TBXAS1 (0.69) | TBXAS1 | |
| SCHEMBL8308559 | 0.78 | TBXAS1 (0.58) | TBXAS1 | |
| SCHEMBL8443313 | 0.78 | TBXAS1 (0.73) | TBXAS1 | |
| SCHEMBL10836333 | 0.77 | TBXAS1 (0.71) | TBXAS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579618-B1 | PYRIDINE- AND IMIDAZOLE-DERIVED AGENTS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1999-10-13 | — | — | EP | disclosed |
| US-5705523-A | THROMBOXANE A2 SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5457118-A | Pyridine derived agents for cardiovascular diseases | PFIZER INC. (US) | 1995-10-10 | — | — | US | disclosed |